• Users Online: 218
RESEARCH ARTICLE
Year : 2014  |  Volume : 2  |  Issue : 2  |  Page : 8

Is there any positive remodeling after enhanced external counter pulsation in patients with severe refractory angina?


1 Rajaie Cardiovascular, Medical and Research Center, Iran University of Medical Sciences, Tehran, IR Iran
2 Madani Cardiovascular, Medical and Research Center, Tabriz University of Medical Sciences, Tabriz, IR Iran
3 Rajaie Cardiovascular, Medical and Research Center, Echocardiography Lab, Iran University of Medical Sciences, Tehran, IR Iran
4 Cardiology Department, Urmia University of Medical Sciences, Urmia, IR Iran
5 Cardiology Department, Erfan General Hospital, Tehran, IR Iran
6 Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
7 Cardiology Department, Isfahan University of Medical Sciences, Isfahan, IR Iran

Correspondence Address:
Naser Aslanabadi
Madani Cardiovascular, Medical and Research Center, Tabriz University of Medical Sciences, Tabriz
IR Iran
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.5812/acvi.20798

Rights and Permissions

Background: Patients with severe refractory cardiac angina who are not candidates for any form of invasive treatment and are already on optimal medical therapy have few therapeutic options. Enhanced external counter pulsation (EECP) offers an alternative palliative and possibly therapeutic option for these patients. EECP achieves this by inducing hemodynamic effects much similar to those of the intraaortic balloon pump. Objectives: We sought to further evaluate these therapeutic effects, especially on the basis of echocardiographic data. Patients and Methods: Thirty-two patients who had severe refractory angina despite full anti-ischemic medication and were poor candidates for invasive procedures were evaluated. After undergoing 35 sessions of EECP, the patients were followed up for 6 months for adverse events, change in quality of life, severity of the remaining symptoms according to the Canadian Cardiovascular Society (CCS) classification, and echocardiographic changes. Results: After receiving standard EECP treatment regimen, the patients showed a marked increase in quality of life scores; a significant decrease in left ventricular (LV) end-diastolic volume index after 6 months (P = 0.045), in tandem with an increase in the LV myocardial performance index (P = 0.04) with no significant change in the LV ejection fraction; and a significant decrease in the CCS scores (P = 0.01). In addition, physical performance measures, including time to unset of angina during the exercise test, were significantly increased. Conclusions: EECP is a useful and low-risk additive therapeutic option in patients with end-stage and non-responsive angina symptoms who are receiving optimal medical conventional treatments and are not good candidates for invasive procedures. This treatment can induce some positive remodeling in the LV.


[PDF]*
    
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
  • Kiavar M
  • Aslanabadi N
  • Alizadehasl A
  • Pournaky AA
  • Hashemi A
  • Salehi R
  • Chitsazan M
  • Nourbakhsh S
  • Esfahani MA
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed427    
    Printed49    
    Emailed0    
    PDF Downloaded71    
    Comments [Add]    

Recommend this journal